WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_GGGAGGRR_V$MAZ_Q6       ID:DB_ID:2430
C=2250; O=27; E=5.06; R=5.34; rawP=4.23e-13; adjP=1.17e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000030582 NA GRN granulin 2896 ENSG00000030582
2  ENSG00000102287 NA GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2564 ENSG00000102287
3  ENSG00000198467 NA TPM2 tropomyosin 2 (beta) 7169 ENSG00000198467
4  ENSG00000126458 NA RRAS related RAS viral (r-ras) oncogene homolog 6237 ENSG00000126458
5  ENSG00000159251 NA ACTC1 actin, alpha, cardiac muscle 1 70 ENSG00000159251
6  ENSG00000243667 NA WDR92 WD repeat domain 92 116143 ENSG00000243667
7  ENSG00000075785 NA RAB7A RAB7A, member RAS oncogene family 7879 ENSG00000075785
8  ENSG00000166317 NA SYNPO2L synaptopodin 2-like 79933 ENSG00000166317
9  ENSG00000165996 NA PTPLA protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A 9200 ENSG00000165996
10  ENSG00000082014 NA SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 6604 ENSG00000082014
11  ENSG00000177791 NA MYOZ1 myozenin 1 58529 ENSG00000177791
12  ENSG00000175048 NA ZDHHC14 zinc finger, DHHC-type containing 14 79683 ENSG00000175048
13  ENSG00000077782 NA FGFR1 fibroblast growth factor receptor 1 2260 ENSG00000077782
14  ENSG00000177606 NA JUN jun proto-oncogene 3725 ENSG00000177606
15  ENSG00000129170 NA CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 8048 ENSG00000129170
16  ENSG00000154736 NA ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 11096 ENSG00000154736
17  ENSG00000157540 NA DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1859 ENSG00000157540
18  ENSG00000197361 NA FBXL22 F-box and leucine-rich repeat protein 22 283807 ENSG00000259662 ENSG00000197361
19  ENSG00000196428 NA TSC22D2 TSC22 domain family, member 2 9819 ENSG00000196428
20  ENSG00000140285 NA FGF7 fibroblast growth factor 7 2252 ENSG00000140285
21  ENSG00000213639 NA PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 5500 ENSG00000213639
22  ENSG00000088930 NA XRN2 5'-3' exoribonuclease 2 22803 ENSG00000088930
23  ENSG00000134121 NA CHL1 cell adhesion molecule with homology to L1CAM (close homolog of L1) 10752 ENSG00000134121
24  ENSG00000168610 NA STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 6774 ENSG00000168610
25  ENSG00000125648 NA SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 79085 ENSG00000125648
26  ENSG00000092068 NA SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 23428 ENSG00000092068
27  ENSG00000170577 NA SIX2 SIX homeobox 2 10736 ENSG00000170577


Database:Transcription Target       Name:hsa_V$MEF2_01       ID:DB_ID:1852
C=142; O=8; E=0.32; R=25.05; rawP=1.28e-09; adjP=1.77e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000177606 NA JUN jun proto-oncogene 3725 ENSG00000177606
2  ENSG00000114854 NA TNNC1 troponin C type 1 (slow) 7134 ENSG00000114854
3  ENSG00000198467 NA TPM2 tropomyosin 2 (beta) 7169 ENSG00000198467
4  ENSG00000147573 NA TRIM55 tripartite motif containing 55 84675 ENSG00000147573
5  ENSG00000166317 NA SYNPO2L synaptopodin 2-like 79933 ENSG00000166317
6  ENSG00000149596 NA JPH2 junctophilin 2 57158 ENSG00000149596
7  ENSG00000091482 NA SMPX small muscle protein, X-linked 23676 ENSG00000091482
8  ENSG00000111245 NA MYL2 myosin, light chain 2, regulatory, cardiac, slow 4633 ENSG00000111245


Database:Transcription Target       Name:hsa_V$MEF2_02       ID:DB_ID:2007
C=226; O=9; E=0.51; R=17.71; rawP=2.43e-09; adjP=2.24e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000177606 NA JUN jun proto-oncogene 3725 ENSG00000177606
2  ENSG00000114854 NA TNNC1 troponin C type 1 (slow) 7134 ENSG00000114854
3  ENSG00000129170 NA CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 8048 ENSG00000129170
4  ENSG00000197361 NA FBXL22 F-box and leucine-rich repeat protein 22 283807 ENSG00000259662 ENSG00000197361
5  ENSG00000198467 NA TPM2 tropomyosin 2 (beta) 7169 ENSG00000198467
6  ENSG00000159251 NA ACTC1 actin, alpha, cardiac muscle 1 70 ENSG00000159251
7  ENSG00000166317 NA SYNPO2L synaptopodin 2-like 79933 ENSG00000166317
8  ENSG00000091482 NA SMPX small muscle protein, X-linked 23676 ENSG00000091482
9  ENSG00000111245 NA MYL2 myosin, light chain 2, regulatory, cardiac, slow 4633 ENSG00000111245


Database:Transcription Target       Name:hsa_V$SRF_Q6       ID:DB_ID:1975
C=239; O=9; E=0.54; R=16.74; rawP=3.97e-09; adjP=2.74e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114854 NA TNNC1 troponin C type 1 (slow) 7134 ENSG00000114854
2  ENSG00000101335 NA MYL9 myosin, light chain 9, regulatory 10398 ENSG00000101335
3  ENSG00000197361 NA FBXL22 F-box and leucine-rich repeat protein 22 283807 ENSG00000259662 ENSG00000197361
4  ENSG00000198467 NA TPM2 tropomyosin 2 (beta) 7169 ENSG00000198467
5  ENSG00000159251 NA ACTC1 actin, alpha, cardiac muscle 1 70 ENSG00000159251
6  ENSG00000147573 NA TRIM55 tripartite motif containing 55 84675 ENSG00000147573
7  ENSG00000149596 NA JPH2 junctophilin 2 57158 ENSG00000149596
8  ENSG00000161202 NA DVL3 dishevelled, dsh homolog 3 (Drosophila) 1857 ENSG00000161202
9  ENSG00000170577 NA SIX2 SIX homeobox 2 10736 ENSG00000170577


Database:Transcription Target       Name:hsa_YTATTTTNR_V$MEF2_02       ID:DB_ID:2431
C=691; O=13; E=1.55; R=8.36; rawP=5.57e-09; adjP=3.07e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000177606 NA JUN jun proto-oncogene 3725 ENSG00000177606
2  ENSG00000114854 NA TNNC1 troponin C type 1 (slow) 7134 ENSG00000114854
3  ENSG00000129170 NA CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 8048 ENSG00000129170
4  ENSG00000197361 NA FBXL22 F-box and leucine-rich repeat protein 22 283807 ENSG00000259662 ENSG00000197361
5  ENSG00000159251 NA ACTC1 actin, alpha, cardiac muscle 1 70 ENSG00000159251
6  ENSG00000136631 NA VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 11311 ENSG00000136631
7  ENSG00000149596 NA JPH2 junctophilin 2 57158 ENSG00000149596
8  ENSG00000160712 NA IL6R interleukin 6 receptor 3570 ENSG00000160712
9  ENSG00000091482 NA SMPX small muscle protein, X-linked 23676 ENSG00000091482
10  ENSG00000111245 NA MYL2 myosin, light chain 2, regulatory, cardiac, slow 4633 ENSG00000111245
11  ENSG00000092068 NA SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 23428 ENSG00000092068
12  ENSG00000118518 NA RNF146 ring finger protein 146 81847 ENSG00000118518
13  ENSG00000162627 NA SNX7 sorting nexin 7 51375 ENSG00000162627


Database:Transcription Target       Name:hsa_V$HMEF2_Q6       ID:DB_ID:2074
C=136; O=7; E=0.31; R=22.88; rawP=2.69e-08; adjP=1.24e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000177606 NA JUN jun proto-oncogene 3725 ENSG00000177606
2  ENSG00000114854 NA TNNC1 troponin C type 1 (slow) 7134 ENSG00000114854
3  ENSG00000111245 NA MYL2 myosin, light chain 2, regulatory, cardiac, slow 4633 ENSG00000111245
4  ENSG00000091482 NA SMPX small muscle protein, X-linked 23676 ENSG00000091482
5  ENSG00000198467 NA TPM2 tropomyosin 2 (beta) 7169 ENSG00000198467
6  ENSG00000166317 NA SYNPO2L synaptopodin 2-like 79933 ENSG00000166317
7  ENSG00000149596 NA JPH2 junctophilin 2 57158 ENSG00000149596


Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=23; E=6.50; R=3.54; rawP=8.16e-08; adjP=3.22e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115109 NA EPB41L5 erythrocyte membrane protein band 4.1 like 5 57669 ENSG00000115109
2  ENSG00000198467 NA TPM2 tropomyosin 2 (beta) 7169 ENSG00000198467
3  ENSG00000129055 NA ANAPC13 anaphase promoting complex subunit 13 25847 ENSG00000129055
4  ENSG00000126458 NA RRAS related RAS viral (r-ras) oncogene homolog 6237 ENSG00000126458
5  ENSG00000137845 NA ADAM10 ADAM metallopeptidase domain 10 102 ENSG00000137845
6  ENSG00000143198 NA MGST3 microsomal glutathione S-transferase 3 4259 ENSG00000143198
7  ENSG00000139641 NA ESYT1 extended synaptotagmin-like protein 1 23344 ENSG00000139641
8  ENSG00000080815 NA PSEN1 presenilin 1 5663 ENSG00000080815
9  ENSG00000167216 NA KATNAL2 katanin p60 subunit A-like 2 83473 ENSG00000167216
10  ENSG00000077782 NA FGFR1 fibroblast growth factor receptor 1 2260 ENSG00000077782
11  ENSG00000065923 NA SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 84679 ENSG00000065923
12  ENSG00000129472 NA RAB2B RAB2B, member RAS oncogene family 84932 ENSG00000129472
13  ENSG00000135506 NA OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 10956 ENSG00000135506
14  ENSG00000177606 NA JUN jun proto-oncogene 3725 ENSG00000177606
15  ENSG00000145349 NA CAMK2D calcium/calmodulin-dependent protein kinase II delta 817 ENSG00000145349
16  ENSG00000129170 NA CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 8048 ENSG00000129170
17  ENSG00000154736 NA ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 11096 ENSG00000154736
18  ENSG00000196428 NA TSC22D2 TSC22 domain family, member 2 9819 ENSG00000196428
19  ENSG00000088930 NA XRN2 5'-3' exoribonuclease 2 22803 ENSG00000088930
20  ENSG00000089597 NA GANAB glucosidase, alpha; neutral AB 23193 ENSG00000089597
21  ENSG00000125648 NA SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 79085 ENSG00000125648
22  ENSG00000092068 NA SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 23428 ENSG00000092068
23  ENSG00000115539 NA PDCL3 phosducin-like 3 79031 ENSG00000115539


Database:Transcription Target       Name:hsa_V$SRF_C       ID:DB_ID:1997
C=209; O=7; E=0.47; R=14.89; rawP=5.04e-07; adjP=1.70e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114854 NA TNNC1 troponin C type 1 (slow) 7134 ENSG00000114854
2  ENSG00000101335 NA MYL9 myosin, light chain 9, regulatory 10398 ENSG00000101335
3  ENSG00000161202 NA DVL3 dishevelled, dsh homolog 3 (Drosophila) 1857 ENSG00000161202
4  ENSG00000197361 NA FBXL22 F-box and leucine-rich repeat protein 22 283807 ENSG00000259662 ENSG00000197361
5  ENSG00000159251 NA ACTC1 actin, alpha, cardiac muscle 1 70 ENSG00000159251
6  ENSG00000147573 NA TRIM55 tripartite motif containing 55 84675 ENSG00000147573
7  ENSG00000149596 NA JPH2 junctophilin 2 57158 ENSG00000149596


Database:Transcription Target       Name:hsa_V$RSRFC4_Q2       ID:DB_ID:2075
C=212; O=7; E=0.48; R=14.68; rawP=5.55e-07; adjP=1.70e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114854 NA TNNC1 troponin C type 1 (slow) 7134 ENSG00000114854
2  ENSG00000111245 NA MYL2 myosin, light chain 2, regulatory, cardiac, slow 4633 ENSG00000111245
3  ENSG00000091482 NA SMPX small muscle protein, X-linked 23676 ENSG00000091482
4  ENSG00000198467 NA TPM2 tropomyosin 2 (beta) 7169 ENSG00000198467
5  ENSG00000159251 NA ACTC1 actin, alpha, cardiac muscle 1 70 ENSG00000159251
6  ENSG00000147573 NA TRIM55 tripartite motif containing 55 84675 ENSG00000147573
7  ENSG00000143198 NA MGST3 microsomal glutathione S-transferase 3 4259 ENSG00000143198


Database:Transcription Target       Name:hsa_V$SRF_Q4       ID:DB_ID:2286
C=220; O=7; E=0.49; R=14.15; rawP=7.11e-07; adjP=1.96e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114854 NA TNNC1 troponin C type 1 (slow) 7134 ENSG00000114854
2  ENSG00000101335 NA MYL9 myosin, light chain 9, regulatory 10398 ENSG00000101335
3  ENSG00000161202 NA DVL3 dishevelled, dsh homolog 3 (Drosophila) 1857 ENSG00000161202
4  ENSG00000198467 NA TPM2 tropomyosin 2 (beta) 7169 ENSG00000198467
5  ENSG00000159251 NA ACTC1 actin, alpha, cardiac muscle 1 70 ENSG00000159251
6  ENSG00000140416 NA TPM1 tropomyosin 1 (alpha) 7168 ENSG00000140416
7  ENSG00000149596 NA JPH2 junctophilin 2 57158 ENSG00000149596




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).